NHS Technology Adoption Centre NTAC D-Dimer Implementation Pack published – 24 October 2012

Posted on October 30, 2012. Filed under: Diagnostics | Tags: , , , |

 NHS Technology Adoption Centre NTAC D-Dimer Implementation Pack published – 24 October 2012

The NHS Technology Adoption Centre (NTAC) has published a Technology Implementation Pack which provides NHS organisations information, guidance and financial savings around implementing D-dimer blood testing in the diagnosis of Deep Vein Thrombosis (DVT) in primary care settings.

“Deep Vein Thrombosis (DVT) is the formation of a blood clot in the deep veins of the legs. When testing for a DVT health professionals can use blood tests to determine the presence and concentration of a marker “D-dimer”. This helps to measure whether a clot has formed and is breaking down. There are a number of products currently on the market which are able to detect D-dimer in the blood. Some of these can be used in primary care settings rather than hospital laboratories.

The rationale behind the use of D-dimer testing within a primary care setting is to speed up patient assessment; this enables clinicians to determine which patients should be urgently referred for hospital intervention. It also aims to give optimum care in terms of patient experience by offering care ‘closer to home’ and assisting signposting to other services where appropriate.

Savings generated from introducing this technology are in relation to the reduction in secondary care referrals for suspected DVT. These relate to those patients who are found to be at low risk and can be excluded from the DVT pathway following both a Wells assessment and D-dimer testing.”

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NICE guideline on blood clot prevention – 27 January 2010

Posted on January 28, 2010. Filed under: Surgery | Tags: , , , |

2010/006 New NICE guideline on blood clot prevention will help save thousands of lives

“Thousands of lives could be saved with the help of a new guideline on preventing blood clots in hospital patients, published today (Wednesday 27 January) by the National Institute for Health and Clinical Excellence (NICE).  The guideline focuses on reducing the risk of deep vein thrombosis (blood clots blocking veins, also commonly known as DVT) in patients admitted to hospital.  If a blood clot breaks away it may travel to the lungs and cause a blockage – a potentially fatal pulmonary embolism.   Venous thromboembolism (VTE) covers both DVT and its possible consequence pulmonary embolism – the guideline sets out simple steps to help prevent VTE and therefore help save lives.

An estimated 25,000 people who are admitted to hospital die from preventable venous thromboembolism each year.  The NICE guideline, jointly developed with the National Clinical Guideline Centre for Acute and Chronic Conditions, recommends that all patients should be assessed for risk of developing blood clots on admission to hospital, and then given preventative treatment that suits their individual needs. Options include blood-thinning drugs such as heparin, anti-embolism stockings and foot impulse or pneumatic devices.  Importantly, this advice covers all patients admitted to hospital – including those having day-case procedures – and not just those patients having surgery.”

See the NICE VTE guideline

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Venous thromboembolism prevention: a patient safety priority – UK – 25 June 2009

Posted on June 26, 2009. Filed under: Cardiol / Cardiothor Surg, Patient Safety | Tags: |

Venous thromboembolism prevention: a patient safety priority

Document type:      Reference
Author:     Edited by Dr Roopen Arya BMBCh MA PhD FRCP FRCPath, Director, King’s Thrombosis Centre
Published date:      25 June 2009
Pages:      42

“Resource document issued at the Leadership Summit: Venous Thromboembolism in the NHS, convened by the Chief Medical Officer and the All-Party Parliamentary Thrombosis Group”

DoH Publications

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Outcomes of Genetic Testing in Adults with a History of Venous Thromboembolism. Evidence Report/Technology Assessment – AHRQ – June 2009

Posted on June 25, 2009. Filed under: Cardiol / Cardiothor Surg, Genomics | Tags: , |

AHRQ = US Agency for Healthcare Research & Quality

Segal JB, Brotman DJ, Emadi A, Necochea AJ, Samal L, Wilson LM, Crim MT, Bass EB.
Outcomes of Genetic Testing in Adults with a History of Venous Thromboembolism. Evidence Report/Technology Assessment No. 180. (Prepared by Johns Hopkins University Evidence-based Practice Center under contract no. HHSA 290-2007-10061-I). AHRQ Publication No. 09-E011. Rockville, MD. Agency for Healthcare Research and Quality.Value of Genetic Testing for Preventing Blood Clots Unproven

AHRQ released a new evidence report that found insufficient evidence to conclude that genetic testing for two gene mutations in adults with a history of blood clots helps to prevent a condition known as deep-vein thrombosis or to improve other clinical outcomes.  The report, a summary of which will be published in the June 17 issue of JAMA, also failed to find any benefit from genetic testing of family members of patients who have at least one of the two mutations — known as Factor V Leiden (FVL) and prothrombin G20210A — as well as a history of deep-vein thrombosis.   The evidence report was requested and supported by CDC’s Office of Public Health Genomics (OPHG).  The Evaluation of Geno mic Applications in Practice and Prevention Working Group, established by OPHG in 2005, will use this evidence report and other evidence to make recommendations on the validity and utility of genetic tests for FVL and prothrombin G20210A. This report, titled Outcomes of Genetic Testing in Adults with a History of Venous Thromboembolism, was conducted by AHRQ’s Johns Hopkins Evidence-based Practice Center in Baltimore.

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