Initial National Priorities for Comparative Effectiveness Research – Institute of Medicine (US) – 30 June 2009

Posted on July 1, 2009. Filed under: Health Systems Improvement, Research | Tags: , , , , , |

Initial National Priorities for Comparative Effectiveness Research – Institute of Medicine (US) – 30 June 2009

Full text of the report from National Academies Press

“Clinical research presents health care providers with information on the natural history and clinical presentations of disease as well as diagnostic and treatment options. Consumers, patients, and caregivers also require this information to decide how to evaluate and treat their conditions. All too often, the information necessary to inform these medical decisions is incomplete or unavailable, resulting in more than half of the treatments delivered today lacking clear evidence of effectiveness.

Comparative effectiveness research (CER) identifies what works best for which patients under what circumstances. Congress, in the American Recovery and Reinvestment Act (ARRA) of 2009, tasked the Institute of Medicine (IOM) to recommend national priorities for research questions to be addressed by CER and supported by ARRA funds. In its 2009 report, Initial National Priorities for Comparative Effectiveness Research, the authoring committee establishes a working definition of CER, develops a priority list of research topics to be undertaken with ARRA funding using broad stakeholder input, and identifies the necessary requirements to support a robust and sustainable CER enterprise. The full list of priorities and recommendations can be found in the below report brief.”

2 articles on this from the NEJM – 30 June 2009

Prioritizing Comparative-Effectiveness Research — IOM Recommendations
J.K. Iglehart

Comparative-Effectiveness Research — Implications of the Federal Coordinating Council’s Report
P.H. Conway and C. Clancy

2 articles from the Annals of Internal Medicine

Comparative Effectiveness Research: A Report From the Institute of Medicine
Harold C. Sox, MD, Editor, and Sheldon Greenfield, MD
4 August 2009  Volume 151 Issue 3  Annals of Internal Medicine

Rethinking Randomized Clinical Trials for Comparative Effectiveness Research: The Need for Transformational Change
Bryan R. Luce, PhD, MBA; Judith M. Kramer, MD, MS; Steven N. Goodman, MD, MHS, PhD; Jason Connor, PhD; Sean Tunis, MD, MSc; Danielle Whicher, MHS; and J. Sanford Schwartz, MD
4 August 2009  Volume 151 Issue 3    Annals of Internal Medicine

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