Treatment Strategies for Women With Coronary Artery Disease – Agency for Healthcare Research and Quality [US] – August 2012

Posted on August 30, 2012. Filed under: Cardiol / Cardiothor Surg, Comparative Effectiveness Research | Tags: |

Treatment Strategies for Women With Coronary Artery Disease – Agency for Healthcare Research and Quality [US] – August 2012

Dolor RJ, Melloni C, Chatterjee R, Allen LaPointe NM, Williams JB Jr., Coeytaux RR, McBroom AJ, Musty MD, Wing L, Samsa GP, Patel MR.
Treatment Strategies for Women With Coronary Artery Disease. Comparative Effectiveness Review No. 66.
(Prepared by the Duke Evidence-based Practice Center under Contract No. 290-2007-10066-I.) AHRQ Publication No. 12-EHC070-EF Rockville, MD. Agency for Healthcare Research and Quality. August 2012

“Structured Abstract

Objectives. Although coronary artery disease (CAD) is the leading cause of death for women in the United States, treatment studies to date have primarily enrolled men and may not reflect the benefits and risks that women experience. Our systematic review of the medical literature assessed the comparative effectiveness of major treatment options for CAD specifically in women. The comparisons were (1) percutaneous coronary intervention (PCI) versus fibrinolysis/supportive pharmacologic therapy in ST elevation myocardial infarction (STEMI), (2) early invasive versus initial conservative management in non-ST elevation myocardial infarction (NSTEMI) or unstable angina, and (3) PCI versus coronary artery bypass surgery (CABG) versus optimal medical therapy in stable or unstable angina. The endpoints assessed were clinical outcomes, modifiers of effectiveness by demographic and clinical factors, and safety outcomes.”

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