Redesigning the Clinical Effectiveness Research Paradigm: Innovation and Practice-Based Approaches – Workshop Summary – Institute of Medicine – 6 December 2010

Posted on January 19, 2011. Filed under: Comparative Effectiveness Research, Research | Tags: , |

Redesigning the Clinical Effectiveness Research Paradigm: Innovation and Practice-Based Approaches – Workshop Summary – Institute of Medicine – 6 December 2010

“Currently, a substantial gap exists between the knowledge needed and that available for medical care decisions—and that gap is growing larger. Approaches to clinical research are being substantially outpaced by the rapid growth in new health care diagnostic and treatment options and an explosion of new genetics insights that hold real implications for the potential – and the need – to personalize individual interventions. Advances in informatics, large scale data sets, and clinical research methods to assess those data sets hold promise for considerably accelerating the pace, reliability, and applicability of clinical effectiveness research. 

To help consider these issues, the IOM Roundtable on Value & Science-Driven Health Care sponsored a meeting to explore the methods, data resources, tools, and techniques that are emerging in the new generation of accelerated clinical research approaches.  This publication of the discussions, Redesigning the Clinical Effectiveness Research Paradigm: Innovation and Practice-Based Approaches, summarizes issues related to the magnitude of the need for better information, the opportunities to align research and practice, and the potential for emerging research and data networks, innovative approaches to study design, analysis, and modeling.  This publication is the most recent in the Roundtable’s Learning Health System Series in which each volume represents a basic element in the movement towards a system in which progress in science, informatics, and care culture align to generate new knowledge as an ongoing and natural by-product of the care experience, and to seamlessly refine and deliver best practices for continuous improvement in health and health care.”

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